A Chance to Expand Your Vocabulary

“Personalized medicine” is a phrase we are going to hear a lot more about in the future.

Recently I have attended meetings or picked up articles about “personalized medicine.” It seems like many people are beginning to use the term in different contexts. Some use the term to refer to high-end concierge medical practices in which a patient pays a primary care physician an annual “membership” fee. But, the term conveys far more power and has implications for many of us.

Last year I had the opportunity to talk with Dr. Bill Nelson, Professor and Director of the Sidney Kimmel Cancer Center at Johns Hopkins. He explained that “within the next few years, all cancer patients at the Kimmel Cancer Center will have their tumors analyzed to reveal a unique “fingerprint.” The fingerprint represents the combination of genetic alterations specific to each person’s cancer. Just as every person is genetically unique, so is every cancer. Targeting these alterations, say scientists, will improve treatment outcomes, thwart cancers before they develop, and slash the costs of new drug discovery.”

The new edition of the Hopkins publication, Promise and Progress, describes how The Johns Hopkins Kimmel Cancer Center is translating laboratory discoveries into remarkable new therapies that target the unique cellular characteristics of each patient’s cancer. [ http://www.hopkinsmedicine.org/news/publications/promise_progress/the_time_is_now_2010_2011_/personalized_medicine_is_here_the_time_is_now].

Personalized medicine may sound like a simple concept, but the science behind it may change the course of cancer treatment. Like me, you may want to add the phrase to your lexicon.

Numbers

I always liked math—algebra withstanding. But with each year I come to better appreciate the importance of numbers. Although April 15 has just passed, remember that numbers have a pervasive impact on our health as well as our taxes. Whether we want to admit it or not, our increasing age impacts our health and our daily lives. More important, however, is our “medical age.”

Most of us know our shoe size or dress size, but do you know your HLD and LDL cholesterol, your glucose level or blood pressure? How many grams of fiber are you eating a day? What is your thyroid level? Yesterday I learned from a Johns Hopkins ophthalmologist that, on average, with each advancing decade the vitreous gel that fills your eye pulls away from your retina by 10 percent. I wondered what other changes are occurring in my body that can be captured by data.

We may not be doctors, but we need to become familiar with these numbers and know how they can impact our health.

Sunshine and Inspiration

After months of planning, the staff and I were finally departing for south Florida to bring A Woman's Journey to women in Palm Beach and Naples. When the captain informed us that we would sit on the tarmac for 30 minutes, I turned on my phone and found a message from Lillie Shockney, the scheduled keynote speaker for A Woman's Journey Palm Beach. Lillie had food poisoning and would not make the conference. I looked around at the other passengers and spotted some Hopkins colleagues. By the time we took off, we had invited the new president of the Johns Hopkins University to be a keynote speaker.

Ron Daniels, who had been installed in the fall as JHU's 14 president, was amazing. I am so grateful that he was willing to speak about the university and his self-described walk-abouts throughout Johns Hopkins. In particular, President Daniels described his tour of The Johns Hopkins Hospital operating rooms and the opportunity to witness a Whipple procedure. The Whipple is a surgical procedure that was developed to remove pancreatic and other GI tumors. According to President Daniels, when Johns Hopkins surgeon Dr. John Cameron began his career, the mortality rate from the surgery was nearly 30 percent. Since then Dr. Cameron has worked to improve the Whipple procedure and reduce the mortality rate to nearly 1%. Just days after observing this procedure, President Daniels was diagnosed with a rare type of tumor in the intestine. As we all learned, the tumor was removed through a Whipple procedure. Fortunately, President Daniels' prognosis is excellent.

The presentation was a most inspiring conclusion to a terrific Woman's Journey in Palm Beach. Surely we will return next year. I hope those of you living in south Florida will join us.
Leslie